Does CBD help with Alzheimer’s disease?

Research on the effects of CBD on Alzheimer’s disease is still in its early stages, but due to the significant increase in life expectancy, the need to study this disease has increased. Some initial scientific research is encouraging.

Let’s take a closer look!

https://www.sciencedaily.com/releases/2021/03/210309192548.htm  from March 2021 “CBD reduces plaque, improves cognition in model of familial Alzheimer’s”

This study found that high doses of CBD oil given to people with advanced Alzheimer’s increased protein levels, which play a key role in removing plaque from the brain.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970569/ from December 2019 “A Review on Studies of Marijuana for Alzheimer’s Disease – Focusing on CBD, THC”

Studies show that CBD can help suppress the factors that cause Alzheimer’s disease, the effectiveness of the oil is enhanced when combined and that it may be more effective when used in combination with THC.

https://pubmed.ncbi.nlm.nih.gov/28981597/ October 2017 “Effects of cannabidiol interactions with Wnt/β-catenin pathway and PPARγ on oxidative stress and neuroinflammation in Alzheimer’s disease”

CBD attenuates oxidative stress and diminishes mitochondrial dysfunction and reactive oxygen species generation. CBD suppresses, through activation of PPARγ, pro-inflammatory signaling and may be a potential new candidate for AD therapy.

https://pubmed.ncbi.nlm.nih.gov/28025562/ “Cannabidiol Modulates the Expression of Alzheimer’s Disease-Related Genes in Mesenchymal Stem Cells” Conclusion is that GMSCs preconditioned with CBD possess a molecular profile that might be more beneficial for the treatment of AD.

Also CBD products help reduce Trusted Source inflammation and insomnia.
A study into the effects of nabilone, a cannabinoid-based medication approved for treating nausea in people undergoing chemotherapy, found that it reduced agitation and improved behavior in individuals with dementia.