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    Leaf Boutique
    Neonatal Cannabidiol Exposure Impairs Spatial Memory and Disrupts Neuronal Dendritic Morphology in Young Adult Rats ... See MoreSee Less

    Neonatal Cannabidiol Exposure Impairs Spatial Memory and Disrupts Neuronal Dendritic Morphology in Young Adult Rats | Cannabis and Cannabinoid Research

    www.liebertpub.com

    Introduction: Early life is a sensitive period for brain development. Perinatal exposure to cannabis is increasingly linked to disruption of neurodevelopment; however, research on the effects of canna...
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    28 Set

    Cannabis Use and Cannabidiol Modulate HIV-Induced Alterations in TREM2 Expression: Implications for Age-Related Neuropathogenesis #mdpiviruses via @VirusesMDPI

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    Synthesis of (-)-Cannabidiol (CBD), (-)-Ξ”9- and (-)-Ξ”8-Tetrahydrocannabinols, Encapsulation of CBD with Nanoparticl…

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    cannabis___chronicles

    cannabis___chronicles
    πŸ“° Unlocking Nature's Cure: Cannabinoids Found t πŸ“° Unlocking Nature's Cure: Cannabinoids Found to Be Breast Cancer Breakthroughs! 🚨 Breakthrough discovery! πŸ’‘ Scientists have identified potential new treatments for breast cancer using minor cannabinoids. Here are the highlights: β€’ Researchers tested 129 phytocannabinoids on estrogen receptor-positive breast cancer cells β€’ Some cannabinoids showed promise as ERΞ± antagonists, meaning they could block or reverse the effects of estrogen on cancer cells β€’ Others acted as ER agonists, stimulating the growth of cancer cells (not ideal!) β€’ Cannabinoids also appeared to inhibit aromatase and AR antagonists with inverse agonist action This study offers new hope for breast cancer patients and highlights the potential benefits of cannabinoids in cancer therapy. Could these natural compounds be the key to overcoming resistance and improving treatment outcomes? πŸ€”πŸ’Š
    πŸ“° Unlocking the Gut-Brain Link: Schizophrenia's πŸ“° Unlocking the Gut-Brain Link: Schizophrenia's Hidden Connection Revealed! πŸ§ πŸ’‘ Breaking News! Researchers uncover potential link between microbiome & schizophrenia! 🀯 In a groundbreaking study, scientists explored the connection between gut health, GABA, and mental illness. They analyzed 30 patients with schizophrenia and 14 healthy controls to identify key differences in their gut microbiota and metabolomes. Key Highlights: ✨ Patients not taking GABA-enhancing medications showed similar gut profiles as healthy controls. ✨ Administration of exogenous GABA improved overall patient homeostasis, beyond just managing symptoms! ✨ The study suggests a link between the microbiome, schizophrenia, and the endo-cannabinoid system. What does this mean? πŸ€” The findings imply that the gut microbiome plays a role in cognitive, emotional, and mental function. Considering medication use is crucial when studying this connection. This research opens doors to new potential treatments for schizophrenia, focusing on gut health and GABA regulation! πŸ’ŠπŸŒ±
    πŸ“° "Warning: Your Next Joint Might be Your Last πŸ“° "Warning: Your Next Joint Might be Your Last - Mental Health Risk on the Rise!" 🚨 Cannabis Use on the Rise: Mental Health Concerns on the Increase! 🚨 β€’ 20% rise in cannabis-related hospital visits in Arizona between 2016-2021. β€’ Rates increased most among adolescents (63.94%) and older adults aged 65+ (84.45%). 🧠 Mind Over Matter? πŸ’” Cannabis-related hospital visits were 7.75 times more likely to be associated with mental health conditions as primary diagnosis. πŸ’‘ The Connection: - Adjusted for other substance use diagnoses, the association increased by a factor of 2.32. - Older adults (65+) are particularly at risk, highlighting the need for prevention and intervention strategies. 🌿 Takeaways: - Increased cannabis use may lead to heightened mental health concerns. - Targeted interventions are crucial for under-recognized populations, especially older adults and adolescents.
    πŸ“° "Trauma Alert: The Hidden Link to Depression πŸ“° "Trauma Alert: The Hidden Link to Depression and Addiction in Young People". Highlighting a crucial link! 🚨 Trauma can have a lasting impact on young people's mental health & substance use patterns. A new study reveals: 🌟 Trauma strongly linked to depressive symptoms and substance use among youth. πŸ’” The nature of this association varies depending on whether alcohol or cannabis is involved. 😞 Young people who experience high levels of trauma tend to struggle with depression for longer. Conclusion: Interventions focused on trauma may be key to helping young people struggling with depression & substance abuse. Let's prioritize their mental health! πŸ€— https://www.leafboutique.eu/trauma-alert-the-hidden-link-to-depression-and-addiction-in-young-people/
    πŸ“° The Pain Relief Revolution: Unleashing the Po πŸ“° The Pain Relief Revolution: Unleashing the Power of Cannabinoids. Highlights: 🌿 Cannabinoids may hold key to managing chronic neuropathic pain πŸ’‘ Endocannabinoid System plays a critical role in regulating pain *The Endocannabinoid System as a Therapeutic Target for Neuropathic Pain: A Review* Researchers have discovered that the Endocannabinoid System (ECS) is crucial in regulating neuropathic pain, and cannabinoids may be an effective treatment option. By understanding how the ECS works, including its receptors, endogenous ligands, and enzymatic routes, scientists can develop innovative therapies for chronic pain. This review bridges the gap between preclinical studies and clinical applications, highlighting the potential of ECS modulation for better pain management outcomes. The study emphasizes the need for high-quality clinical trials to ensure safe and effective integration of cannabinoids into pain management protocols. With further research, cannabinoids may become a valuable tool in managing neuropathic conditions, offering more effective therapies for those suffering from chronic pain. Read more: https://www.leafboutique.eu/the-pain-relief-revolution-unleashing-the-power-of-cannabinoids/
    9 Months of Risk: The Shocking Truth About Prenata 9 Months of Risk: The Shocking Truth About Prenatal Pot Warning Signs Ahead! πŸš¨πŸ‘Ά New research reveals surprising consequences of prenatal cannabis exposure for pregnant women. πŸ‘€ Despite growing cannabis use during pregnancy, many doctors hesitate to discuss potential risks. πŸ’” Studies suggest possible perinatal and long-term neurodevelopmental risks associated with cannabis use. As cannabis policies evolve, it's essential to educate pregnant women about the potential dangers of cannabis use during pregnancy and breastfeeding. A concerted effort to raise awareness could help mitigate these effects. Let's get informed & prioritize healthy pregnancies! πŸ€°πŸΌπŸ’• https://www.leafboutique.eu/9-months-of-risk-the-shocking-truth-about-prenatal-pot/
    πŸ“° High Hopes or Hidden Hurts: What's Behind You πŸ“° High Hopes or Hidden Hurts: What's Behind Your Weed Use? Highlights: 🌟 Cannabis use on the rise among US adults! πŸ’” Coping with bad emotions vs feeling good: what's behind marijuana motives? πŸ” Did you know? πŸ€” People who use cannabis to feel better are more likely to do it frequently, while those trying to cope with emotions might face problems. We investigated how motivations affect feelings and found: Using cannabis for a mood boost actually improves well-being! 🌈 But using it to deal with bad emotions doesn't help and might make things worse. 😞 Conclusion: πŸ‘‰ If you use cannabis, be aware of your motivations! πŸ’‘ Feeling good is one thing, but trying to cope can lead to more issues. Future research will explore these results further. Stay informed! πŸ“š https://pubmed.ncbi.nlm.nih.gov/39311846/
    πŸ“° "Unlocking the Future: CB2 Receptor's Role in πŸ“° "Unlocking the Future: CB2 Receptor's Role in Pain, Inflammation & Disease Revolution! πŸŒΏπŸ”¬βœ¨" ✨ 🌿Recent studies shift focus towards CB2 receptor modulators due to CB1’s psychotropic effects. From 2016-2024, patent reviews reveal exciting advances! πŸ”¬ CB2 agonists show promise in tackling pain, inflammation, arthritis, neuroprotection, and more. Despite challenges, recent ligands boast improved CB2/CB1 selectivity. πŸ”₯ Spotlight on CB2 for diseases like Alzheimer’s, cancer, and osteoporosis. Progress hints at a bright future for CB2-targeted therapies! πŸ’ͺ✨ https://pubmed.ncbi.nlm.nih.gov/39288632/
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